Okay. Two wires, huh? It must be stealing power from the regular doorbell circuit from the doorbell transformer while somehow being able to drive the chime when necessary. But yeah, I think your general idea will work (there seem to be extra crap that needs to be hooked to the nest which I can't guess at).
In other words, wire it up exactly as per Nest instructions exactly like you would a regular doorbell, transformer and all, except instead of wiring to a chime, wire to the coil of a relay. Then hook primary contacts of the relay to your Control4.
**broken link removed**
Basically replacing the chime with a relay in a regular doorbell circuit which should mean that you don't have to worry about what the nest is doing as long as you follow nest's instructions.
Most any relay should work. Just pick one where the control voltage (coil voltage) is the same as your doorbell transformer output voltage.