I have no idea what software you're using to create schematics, but you seem to have different names for the same net????
For example, the "5V+" net appears to also be labeled NetPort6, NetPort1, NetPort42 and NetPort62.
Same thing with the GND net. How in the world do you verify that things are connected correctly?
Doesn't your software complain about the same net having different names? If not, you need to trash it and get something better.
The connection to MCLR/R5 looks to be incorrect, but who could follow that mess?