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I don't know about others, but I do not have proteus, so I cannot open your file to help you. Maybe if you exported the file into a gif or something you might get more response.
I see two problems in your H-bridge:
1) The upper right side optocoupler has a 10k resistor connected to its base instead of to its collector.
2) The high-side Mosfets are N-channel source followers. Then their gate voltage must be 10V higher than the power supply for them to completely turn on.