It's been a while since I designed motherboards and PC systems, but nothing has changed. The rear stake back plates are definitely part of the EMI enclosure. Nothing really to do with static protection. The PC manufacturer designs the case to seal with industry standard rear back plates, and has to (should) test with a variety of boards.
Having said that, are you building a new custom designed system? Or just integrating different third party items like cases, motherboards, and cases? Is this a one time sale, or something that you expect to sell thousands of? If you are selling a single machine, I wouldn't give it a 2nd thought (although I would try to find a suitable plate). If you plan to sell many custom designed systems, then you will need to pass FCC EMI limits, and I doubt you will pass without the back plate (but there are motherboards that are so well deigned from an emissions point of view, that you may). If you are building from standard components, then there should be all the necessary EMI shields included.
Of course the other big question is Class A vs Class B. Much easier to pass if it is for the commercial world and not intended for home use.
JimW