I went to the magazine website, but apparently you have to pay to access the circuits (yeah its listed). You can register, and get access to some circuits and stuff, just not the most recent (or maybe the websit is buggy). Didn't mess around much there.
None of the components in the circuit appear to be consistant with a high power supply (220 in America is used mostly for large appliances). I know very little about 220 mains, except a couple of unfortunate and very unpleasant experiences (are you people nuts or what, the whole house 220 3-phase).
Anyway, try using a 9 volt battery instead of the mains. Hook ip the osciloscope in multisim and see if there is oscillation. Speakers and audio don't simulate well, unless you have a very fast computer.
I did find a Canary Doorbell circuit, had a wav file on the site, sounded pretty cool, might be able to swap a few parts to change the frequency.