Based on the schematic, my guess that there may have been a voltage spike on the AC line, passed thru T1 to the Tinyswitch and blew that. In the process of blowing the Tinyswitch, voltage went from the D pin to the EN/UV pin which then blew the opto isolator.
This assumes the opto isolator pins blown are the detector. If the other LED side is blown, then the "safety" capacitor across the transformer possibly shorted, and blew things on the output side (and LED emitter of optic isolator).
Pin 5 of the Tiny is what seems to have popped, that is the "D" pin, suggesting that is where the high voltage or current occurred...
If the Drain of the device is shorted to the Source, that will be the reason for a fuse blowing.
Just my hunch, maybe someone with better experience with these types of supplies can suggest better options.