if you are processing audio in a circuit in LTSpice, either an amplifier, filter or some effect like fuzz, you can actually input a .wav file, and capture the output as a .wav file. this way you can hear what it sounds like. a couple of things to remember, the input will be limited to +/-1V (2Vp-p), and the output to the output .wav file must be scaled to 1V (2Vp-p). so often, to get the output properly scaled, you may have to look at the waveform at the output in the waveform viewer, and then add an appropriate voltage divider to get the output level for the .wav file within the 1V limit.
the input voltage source is edited by clicking on the text for the voltage parameter and changing the text. since "redhouse2.wav" is too big for me to post here, you will have to provide your own wav file as a source, and edit the parameter line accordingly. the .wav output is a spice directive referencing the output of the voltage divider. this creates a wav file as the circuit simulates.