In my experience, it is only the front and rear indicators that are rated at 21 W. The side repeaters are rated at a much lower power. That is what the data sheet of the IC shows. The flasher units will flash faster when there is only one of the 21 W lamps working. The flashing rate won't change if a side repeater fails, as its current is too small to be noticed.
If you are trying to get the flasher to detect if one of the LED indicators fails, you will have to make sure that the current taken by the side repeater is small compared to what the LED indicators take.
For instance, if you have 2 W LED indicators and still have 5 W side repeaters, the total power will be 2 + 2 + 5 = 9 W. If an indicator fails, the power will drop to 2 + 5 = 7 W. That is only a small ( 22% ) change and it will be difficult to adjust the resistor to get that to work correctly all the time. You have to allow for a change from about 12 V to about 14 V when the engine is running.
If you change the side repeater to LED as well, then it will be much easier to adjust the resistor. With 1 W side repeaters then the normal running is 5 W and a failed indicator will result in 3 W, so that is a 40% change and that is much easier to detect, and is about what the original IC was designed to detect.
You may need to have some resistance, maybe 1 kOhm, in parallel with indicators on each side of the car. The IC detects the start of flashing when the indicator switch is turned on. That is described in the data sheet section 4.7. The potential problem is that LED lights may not conduct at all when there is a low voltage across them, which can make if difficult for the IC to detect that the switch has operated. A resistor may help if that is the case.