If you can assume that you'll never leave fewer than n cars sitting alone on a block, and there will always be n cars, the resistance can be n*1.6k. 10k, for example, would suit a situation where all trains are >5 cars.A single car has to provide a resistance of 1.6 Kohms across the track because that is the very minimum current required to trigger the isolator.
Situations where a train has 4 trailing cars on a block that it was just leaving would be (incorrectly) signaled as an empty block. But an approaching train would see red when it hits this block (since the next one shows occupied), and must stop at least 4 car lengths short of the end.